Metformin for weight loss: honest, modest, and off-label
Metformin is a safe, cheap, well-studied medicine for type 2 diabetes and PCOS, and in diabetes trials it tends to cause slight weight loss rather than weight gain. But in people who do not have diabetes or PCOS, the weight loss from metformin is small and variable, only a few kg over months, and it is not approved as a weight-loss drug. It should not be expected to do what GLP-1 obesity medicines do. Talk to your doctor before using it for weight.
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